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Interactions médicamenteuses

Insulin degludec + Insulin degludec-liraglutide

Gravité: Majeure

Insulin degludec and Insulin degludec-liraglutide: major interaction.

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Résumé

The fixed-dose product already contains insulin degludec, so adding more of it duplicates therapy and raises the risk of hypoglycemia from excess basal insulin.

Ce que signifie cette interaction, en termes simples

Insulin degludec and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Insulin degludec belongs to Endocrine; Insulin degludec-liraglutide belongs to Endocrine.

Niveau de preuve: High

Pourquoi elle survient

Therapeutic duplication leading to additive insulin effect.

Conduite à tenir

Avoid giving separate insulin degludec with the combination product. Use one product and adjust its dose by glucose monitoring.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Insulin degludec with Insulin degludec-liraglutide?

MediHelp rates the interaction as major. Insulin degludec and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. The fixed-dose product already contains insulin degludec, so adding more of it duplicates therapy and raises the risk of hypoglycemia from excess basal insulin.

How serious is the interaction between Insulin degludec and Insulin degludec-liraglutide?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving separate insulin degludec with the combination product. Use one product and adjust its dose by glucose monitoring.

What other medicines interact with Insulin degludec-liraglutide?

MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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