Interactions médicamenteuses
Insulin glargine + Pentamidine
Gravité: Majeure
Insulin glargine and Pentamidine: major interaction.
Dernière mise à jour
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Résumé
Pentamidine can damage pancreatic beta cells, causing an initial hypoglycemia from insulin release, followed by hyperglycemia or diabetes. This makes insulin needs unpredictable.
Ce que signifie cette interaction, en termes simples
Insulin glargine and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin glargine belongs to Endocrine; Pentamidine belongs to Anti Parasitic.
Pourquoi elle survient
Pentamidine is toxic to pancreatic beta cells, causing early insulin release followed by insulin deficiency.
Conduite à tenir
Monitor blood glucose frequently during and after pentamidine therapy and adjust the insulin glargine dose promptly.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Insulin glargine
Autres interactions de Pentamidine
- Clomipramine + Pentamidine Contre-indiquée
- Desipramine + Pentamidine Contre-indiquée
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- Moxifloxacin + Pentamidine Contre-indiquée
- Nortriptyline + Pentamidine Contre-indiquée
- Pentamidine + Pimozide Contre-indiquée
Questions fréquentes
Can I take Insulin glargine with Pentamidine?
MediHelp rates the interaction as major. Insulin glargine and Pentamidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Pentamidine can damage pancreatic beta cells, causing an initial hypoglycemia from insulin release, followed by hyperglycemia or diabetes. This makes insulin needs unpredictable.
How serious is the interaction between Insulin glargine and Pentamidine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose frequently during and after pentamidine therapy and adjust the insulin glargine dose promptly.
What other medicines interact with Insulin glargine?
MediHelp also lists interactions of Insulin glargine with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin glargine page.
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