Interactions médicamenteuses
Leflunomide + Measles mumps rubella and varicella vaccine live
Gravité: Contre-indiquée
Leflunomide and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
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Résumé
This live attenuated combination vaccine may cause disseminated vaccine-strain infection, including varicella, in a patient immunosuppressed by leflunomide. The immune response may also be reduced.
Ce que signifie cette interaction, en termes simples
Leflunomide and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Impaired lymphocyte function reduces control of live attenuated virus replication.
Conduite à tenir
Avoid during leflunomide therapy and until washout is confirmed; vaccinate before treatment starts.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Leflunomide
- Bcg vaccine live + Leflunomide Contre-indiquée
- Influenza virus vaccine quadrivalent intranasal + Leflunomide Contre-indiquée
- Leflunomide + Measles mumps and rubella vaccine live Contre-indiquée
- Leflunomide + Measles vaccine Contre-indiquée
- Leflunomide + Smallpox vaccine live Contre-indiquée
- Alefacept + Leflunomide Majeure
Questions fréquentes
Can I take Leflunomide with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Leflunomide and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine may cause disseminated vaccine-strain infection, including varicella, in a patient immunosuppressed by leflunomide. The immune response may also be reduced.
How serious is the interaction between Leflunomide and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during leflunomide therapy and until washout is confirmed; vaccinate before treatment starts.
What other medicines interact with Leflunomide?
MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Leflunomide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
