Interactions médicamenteuses
Leflunomide + Measles vaccine
Gravité: Contre-indiquée
Leflunomide and Measles vaccine: contraindicated interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Measles vaccine contains live attenuated virus, which may cause disseminated vaccine-strain infection in a patient immunosuppressed by leflunomide. The vaccine response may also be inadequate.
Ce que signifie cette interaction, en termes simples
Leflunomide and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Impaired lymphocyte function reduces control of live attenuated virus replication.
Conduite à tenir
Avoid live vaccines during leflunomide treatment and until drug elimination is confirmed; vaccinate before therapy.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Leflunomide et Measles vaccine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.
Autres interactions de Leflunomide
- Bcg vaccine live + Leflunomide Contre-indiquée
- Influenza virus vaccine quadrivalent intranasal + Leflunomide Contre-indiquée
- Leflunomide + Measles mumps and rubella vaccine live Contre-indiquée
- Leflunomide + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Leflunomide + Smallpox vaccine live Contre-indiquée
- Alefacept + Leflunomide Majeure
Questions fréquentes
Can I take Leflunomide with Measles vaccine?
MediHelp rates the interaction as contraindicated. Leflunomide and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine contains live attenuated virus, which may cause disseminated vaccine-strain infection in a patient immunosuppressed by leflunomide. The vaccine response may also be inadequate.
How serious is the interaction between Leflunomide and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during leflunomide treatment and until drug elimination is confirmed; vaccinate before therapy.
What other medicines interact with Leflunomide?
MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Leflunomide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
