Interazioni tra farmaci
Adenovirus types 4 and 7 live + Certolizumab pegol
Gravità: Controindicata
Adenovirus types 4 and 7 live and Certolizumab pegol: contraindicated interaction.
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Sintesi
The oral adenovirus type 4 and 7 vaccine contains live virus. Under TNF blockade with certolizumab, replication may be poorly controlled, risking vaccine-related infection and a reduced immune response.
Cosa significa questa interazione in parole semplici
Adenovirus types 4 and 7 live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
TNF inhibition impairs immune control of live attenuated virus, raising infection risk and reducing vaccine response.
Cosa fare
Avoid this live vaccine during certolizumab therapy. Vaccinate before starting treatment if indicated, allowing at least 4 weeks.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Certolizumab pegol
- Bcg intravesical live + Certolizumab pegol Controindicata
- Bcg vaccine live + Certolizumab pegol Controindicata
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Controindicata
- Certolizumab pegol + Measles mumps and rubella vaccine Controindicata
- Certolizumab pegol + Measles mumps and rubella vaccine live Controindicata
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live Controindicata
Domande frequenti
Can I take Adenovirus types 4 and 7 live with Certolizumab pegol?
MediHelp rates the interaction as contraindicated. Adenovirus types 4 and 7 live and Certolizumab pegol are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The oral adenovirus type 4 and 7 vaccine contains live virus. Under TNF blockade with certolizumab, replication may be poorly controlled, risking vaccine-related infection and a reduced immune response.
How serious is the interaction between Adenovirus types 4 and 7 live and Certolizumab pegol?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid this live vaccine during certolizumab therapy. Vaccinate before starting treatment if indicated, allowing at least 4 weeks.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Bcg intravesical live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Certolizumab pegol page.
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