Interazioni tra farmaci
Certolizumab pegol + Measles mumps and rubella vaccine live
Gravità: Controindicata
Certolizumab pegol and Measles mumps and rubella vaccine live: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
MMR vaccine contains live attenuated viruses. Certolizumab-induced immunosuppression may allow disseminated vaccine virus infection and reduce the immune response.
Cosa significa questa interazione in parole semplici
Certolizumab pegol and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
TNF inhibition impairs immune control of live attenuated viruses.
Cosa fare
Avoid MMR during certolizumab therapy. Complete live vaccination at least 4 weeks before starting, and check immunity serologically if exposure risk exists.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Controindicata
- Bcg intravesical live + Certolizumab pegol Controindicata
- Bcg vaccine live + Certolizumab pegol Controindicata
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Controindicata
- Certolizumab pegol + Measles mumps and rubella vaccine Controindicata
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live Controindicata
Domande frequenti
Can I take Certolizumab pegol with Measles mumps and rubella vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR vaccine contains live attenuated viruses. Certolizumab-induced immunosuppression may allow disseminated vaccine virus infection and reduce the immune response.
How serious is the interaction between Certolizumab pegol and Measles mumps and rubella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid MMR during certolizumab therapy. Complete live vaccination at least 4 weeks before starting, and check immunity serologically if exposure risk exists.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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