Interazioni tra farmaci
Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal
Gravità: Controindicata
Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
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Sintesi
The intranasal influenza vaccine is a live attenuated product. In patients on certolizumab, the vaccine virus may replicate in an uncontrolled way and cause vaccine-related illness, while immune response may be reduced.
Cosa significa questa interazione in parole semplici
Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
TNF blockade-related immunosuppression reduces control of replicating attenuated influenza virus.
Cosa fare
Use the inactivated injectable influenza vaccine instead of the intranasal live vaccine in patients on certolizumab.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Controindicata
- Bcg intravesical live + Certolizumab pegol Controindicata
- Bcg vaccine live + Certolizumab pegol Controindicata
- Certolizumab pegol + Measles mumps and rubella vaccine Controindicata
- Certolizumab pegol + Measles mumps and rubella vaccine live Controindicata
- Certolizumab pegol + Measles mumps rubella and varicella vaccine live Controindicata
Domande frequenti
Can I take Certolizumab pegol with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine is a live attenuated product. In patients on certolizumab, the vaccine virus may replicate in an uncontrolled way and cause vaccine-related illness, while immune response may be reduced.
How serious is the interaction between Certolizumab pegol and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the inactivated injectable influenza vaccine instead of the intranasal live vaccine in patients on certolizumab.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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