Interazioni tra farmaci
Amlodipine-hydrochlorothiazide-valsartan + Vitamin d
Gravità: Moderata
Amlodipine-hydrochlorothiazide-valsartan and Vitamin d: moderate interaction.
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Sintesi
Thiazide diuretics reduce renal calcium excretion, and vitamin D increases intestinal calcium absorption. Together they may cause hypercalcemia, particularly with high-dose vitamin D or in patients with renal impairment.
Cosa significa questa interazione in parole semplici
Amlodipine-hydrochlorothiazide-valsartan and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Vitamin d belongs to Gastrointestinal Tract.
Perché avviene
Reduced urinary calcium excretion by hydrochlorothiazide combined with increased calcium absorption from vitamin D.
Cosa fare
Monitor serum calcium periodically, especially with high-dose vitamin D or calcium supplements. Reduce the vitamin D dose or review the thiazide if hypercalcemia occurs.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Amlodipine-hydrochlorothiazide-valsartan
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan Controindicata
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide Controindicata
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan Controindicata
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan Maggiore
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan Maggiore
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan Maggiore
Altre interazioni di Vitamin d
- Aluminum hydroxide + Vitamin d Maggiore
- Amlodipine-olmesartan-hydrochlorothiazide + Vitamin d Moderata
- Atenolol-chlorthalidone + Vitamin d Moderata
- Calcium acetate + Vitamin d Moderata
- Calcium carbonate + Vitamin d Moderata
- Calcium chloride + Vitamin d Moderata
Domande frequenti
Can I take Amlodipine-hydrochlorothiazide-valsartan with Vitamin d?
MediHelp rates the interaction as moderate. Amlodipine-hydrochlorothiazide-valsartan and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide diuretics reduce renal calcium excretion, and vitamin D increases intestinal calcium absorption. Together they may cause hypercalcemia, particularly with high-dose vitamin D or in patients with renal impairment.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Vitamin d?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically, especially with high-dose vitamin D or calcium supplements. Reduce the vitamin D dose or review the thiazide if hypercalcemia occurs.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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