Interazioni tra farmaci
Amlodipine-olmesartan-hydrochlorothiazide + Vitamin d
Gravità: Moderata
Amlodipine-olmesartan-hydrochlorothiazide and Vitamin d: moderate interaction.
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Sintesi
Hydrochlorothiazide reduces urinary calcium excretion, and vitamin D enhances intestinal calcium absorption. Together they can cause hypercalcemia, especially with high vitamin D doses, calcium supplements or renal impairment.
Cosa significa questa interazione in parole semplici
Amlodipine-olmesartan-hydrochlorothiazide and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan-hydrochlorothiazide belongs to Cardiovascular; Vitamin d belongs to Gastrointestinal Tract.
Perché avviene
Thiazide-induced renal calcium reabsorption combined with vitamin D-enhanced calcium absorption.
Cosa fare
Monitor serum calcium periodically, particularly with high-dose vitamin D or calcium supplements. Reduce the vitamin D dose or review the thiazide if hypercalcemia develops.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Amlodipine-olmesartan-hydrochlorothiazide
- Aliskiren + Amlodipine-olmesartan-hydrochlorothiazide Controindicata
- Amlodipine-olmesartan-hydrochlorothiazide + Dofetilide Controindicata
- Amlodipine-olmesartan-hydrochlorothiazide + Sparsentan Controindicata
- Acemetacin + Amlodipine-olmesartan-hydrochlorothiazide Maggiore
- Aldesleukin + Amlodipine-olmesartan-hydrochlorothiazide Maggiore
- Amifostine + Amlodipine-olmesartan-hydrochlorothiazide Maggiore
Altre interazioni di Vitamin d
- Aluminum hydroxide + Vitamin d Maggiore
- Amlodipine-hydrochlorothiazide-valsartan + Vitamin d Moderata
- Atenolol-chlorthalidone + Vitamin d Moderata
- Calcium acetate + Vitamin d Moderata
- Calcium carbonate + Vitamin d Moderata
- Calcium chloride + Vitamin d Moderata
Domande frequenti
Can I take Amlodipine-olmesartan-hydrochlorothiazide with Vitamin d?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan-hydrochlorothiazide and Vitamin d can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hydrochlorothiazide reduces urinary calcium excretion, and vitamin D enhances intestinal calcium absorption. Together they can cause hypercalcemia, especially with high vitamin D doses, calcium supplements or renal impairment.
How serious is the interaction between Amlodipine-olmesartan-hydrochlorothiazide and Vitamin d?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium periodically, particularly with high-dose vitamin D or calcium supplements. Reduce the vitamin D dose or review the thiazide if hypercalcemia develops.
What other medicines interact with Amlodipine-olmesartan-hydrochlorothiazide?
MediHelp also lists interactions of Amlodipine-olmesartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-olmesartan-hydrochlorothiazide page.
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