Interazioni tra farmaci
Aripiprazole + Arsenic trioxide
Gravità: Maggiore
Aripiprazole and Arsenic trioxide: major interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Arsenic trioxide causes marked QT prolongation and torsades de pointes. Aripiprazole has a small QT liability, so the effects may be additive, although aripiprazole is among the lower-risk antipsychotics.
Cosa significa questa interazione in parole semplici
Aripiprazole and Arsenic trioxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Aripiprazole belongs to Central Nervous System; Arsenic trioxide belongs to Oncology.
Perché avviene
Additive prolongation of cardiac repolarization.
Cosa fare
Avoid other QT-prolonging drugs during arsenic trioxide therapy where alternatives exist. If aripiprazole must continue, monitor ECG and keep potassium and magnesium within normal range.
Cosa chiedere al farmacista
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Aripiprazole e Arsenic trioxide, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Aripiprazole
- Aripiprazole + Pimozide Controindicata
- Aripiprazole + Thioridazine Controindicata
- Amisulpride + Aripiprazole Maggiore
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Maggiore
- Aripiprazole + Carbamazepine Maggiore
- Aripiprazole + Cisapride Maggiore
Altre interazioni di Arsenic trioxide
- Amiodarone + Arsenic trioxide Controindicata
- Amisulpride + Arsenic trioxide Controindicata
- Arsenic trioxide + Clomipramine Controindicata
- Arsenic trioxide + Dronedarone Controindicata
- Arsenic trioxide + Fluphenazine Controindicata
- Arsenic trioxide + Gemifloxacin Controindicata
Domande frequenti
Can I take Aripiprazole with Arsenic trioxide?
MediHelp rates the interaction as major. Aripiprazole and Arsenic trioxide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Arsenic trioxide causes marked QT prolongation and torsades de pointes. Aripiprazole has a small QT liability, so the effects may be additive, although aripiprazole is among the lower-risk antipsychotics.
How serious is the interaction between Aripiprazole and Arsenic trioxide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid other QT-prolonging drugs during arsenic trioxide therapy where alternatives exist. If aripiprazole must continue, monitor ECG and keep potassium and magnesium within normal range.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
