Interazioni tra farmaci
Aripiprazole + Sufentanil
Gravità: Maggiore
Aripiprazole and Sufentanil: major interaction.
Ultimo aggiornamento Fonti: UK SmPC
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Opioids combined with other CNS depressants increase the risk of profound sedation, respiratory depression and hypotension. Aripiprazole has milder sedative effects but contributes to additive depression.
Cosa significa questa interazione in parole semplici
Aripiprazole and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Aripiprazole belongs to Central Nervous System; Sufentanil belongs to Musculoskeletal.
Perché avviene
Additive CNS and respiratory depression, with additive hypotensive effects.
Cosa fare
Use the lowest effective sufentanil dose and monitor respiratory rate, sedation and blood pressure. Ensure appropriate monitoring and resuscitation capability in procedural settings.
Cosa chiedere al farmacista
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Aripiprazole e Sufentanil, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 7 giorni sul web. Nessuna carta.
Riferimenti
- Abilify 1 mg/mL Oral Solution - SmPC sections 4.3/4.5 (class statement: other CNS medicinal products with overlapping adverse reactions such as sedation; "caution should be used when aripiprazole is administered in combination with alcohol or other CNS medicinal products with overlapping adverse re… — electronic medicines compendium (UK SmPC)
Altre interazioni di Aripiprazole
- Aripiprazole + Pimozide Controindicata
- Aripiprazole + Thioridazine Controindicata
- Amisulpride + Aripiprazole Maggiore
- Aripiprazole + Arsenic trioxide Maggiore
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Maggiore
- Aripiprazole + Carbamazepine Maggiore
Altre interazioni di Sufentanil
- Alprazolam + Sufentanil Maggiore
- Amitriptyline + Sufentanil Maggiore
- Amobarbital + Sufentanil Maggiore
- Asenapine + Sufentanil Maggiore
- Baclofen + Sufentanil Maggiore
- Brexpiprazole + Sufentanil Maggiore
Domande frequenti
Can I take Aripiprazole with Sufentanil?
MediHelp rates the interaction as major. Aripiprazole and Sufentanil can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Opioids combined with other CNS depressants increase the risk of profound sedation, respiratory depression and hypotension. Aripiprazole has milder sedative effects but contributes to additive depression.
How serious is the interaction between Aripiprazole and Sufentanil?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective sufentanil dose and monitor respiratory rate, sedation and blood pressure. Ensure appropriate monitoring and resuscitation capability in procedural settings.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
