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Interazioni tra farmaci

Bacitracin + Valacyclovir

Gravità: Moderata

Bacitracin and Valacyclovir: moderate interaction.

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Sintesi

Systemic bacitracin is nephrotoxic, and with valacyclovir, whose active form acyclovir is renally cleared, kidney injury risk increases. Topical bacitracin has negligible systemic exposure.

Cosa significa questa interazione in parole semplici

Bacitracin and Valacyclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Bacitracin belongs to Miscellaneous; Valacyclovir belongs to Anti Virals.

Livello di evidenza: Low

Perché avviene

Additive nephrotoxicity and reduced renal clearance of acyclovir.

Cosa fare

Avoid systemic bacitracin with valacyclovir where possible. Otherwise maintain hydration, monitor creatinine and adjust valacyclovir dose for renal function.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Bacitracin with Valacyclovir?

MediHelp rates the interaction as moderate. Bacitracin and Valacyclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic bacitracin is nephrotoxic, and with valacyclovir, whose active form acyclovir is renally cleared, kidney injury risk increases. Topical bacitracin has negligible systemic exposure.

How serious is the interaction between Bacitracin and Valacyclovir?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic bacitracin with valacyclovir where possible. Otherwise maintain hydration, monitor creatinine and adjust valacyclovir dose for renal function.

What other medicines interact with Valacyclovir?

MediHelp also lists interactions of Valacyclovir with, for example, Talimogene laherparepvec, Cilastatin-imipenem, Elvitegravir / cobicistat / emtricitabine / tenofovir df. The full list is on the Valacyclovir page.

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