Interazioni tra farmaci
Bcg vaccine live + Prednisolone
Gravità: Controindicata
Bcg vaccine live and Prednisolone: contraindicated interaction.
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Sintesi
BCG is a live attenuated mycobacterium that can cause disseminated BCG disease in immunosuppressed patients, and prednisolone may also reduce the response. This is a risk of serious infection.
Cosa significa questa interazione in parole semplici
Bcg vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Corticosteroid-induced suppression of cell-mediated immunity permits uncontrolled replication of live BCG and reduces vaccine response.
Cosa fare
Do not give BCG during immunosuppressive prednisolone therapy; defer until steroids have been stopped for an adequate interval, per local guidance. Assess alternative TB prevention strategies if indicated.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Prednisolone
- Measles mumps and rubella vaccine live + Prednisolone Controindicata
- Measles mumps rubella and varicella vaccine live + Prednisolone Controindicata
- Measles vaccine + Prednisolone Controindicata
- Mifepristone + Prednisolone Controindicata
- Prednisolone + Radium-223 dichloride Controindicata
- Prednisolone + Rubella vaccine Controindicata
Domande frequenti
Can I take Bcg vaccine live with Prednisolone?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated mycobacterium that can cause disseminated BCG disease in immunosuppressed patients, and prednisolone may also reduce the response. This is a risk of serious infection.
How serious is the interaction between Bcg vaccine live and Prednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during immunosuppressive prednisolone therapy; defer until steroids have been stopped for an adequate interval, per local guidance. Assess alternative TB prevention strategies if indicated.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live, Measles vaccine. The full list is on the Prednisolone page.
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