Interazioni tra farmaci
Measles vaccine + Prednisolone
Gravità: Controindicata
Measles vaccine and Prednisolone: contraindicated interaction.
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Sintesi
Measles vaccine is live attenuated, and in patients on immunosuppressive doses of prednisolone the virus may replicate uncontrollably, causing disseminated vaccine-strain disease. The immune response is also reduced.
Cosa significa questa interazione in parole semplici
Measles vaccine and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and blunts the immune response.
Cosa fare
Avoid live vaccines during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Prednisolone
- Bcg vaccine live + Prednisolone Controindicata
- Measles mumps and rubella vaccine live + Prednisolone Controindicata
- Measles mumps rubella and varicella vaccine live + Prednisolone Controindicata
- Mifepristone + Prednisolone Controindicata
- Prednisolone + Radium-223 dichloride Controindicata
- Prednisolone + Rubella vaccine Controindicata
Domande frequenti
Can I take Measles vaccine with Prednisolone?
MediHelp rates the interaction as contraindicated. Measles vaccine and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated, and in patients on immunosuppressive doses of prednisolone the virus may replicate uncontrollably, causing disseminated vaccine-strain disease. The immune response is also reduced.
How serious is the interaction between Measles vaccine and Prednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
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