Interazioni tra farmaci
Measles mumps rubella and varicella vaccine live + Prednisolone
Gravità: Controindicata
Measles mumps rubella and varicella vaccine live and Prednisolone: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
This live attenuated combination vaccine can cause disseminated vaccine-strain infection, including varicella, in patients on immunosuppressive doses of prednisolone. The immune response is also reduced.
Cosa significa questa interazione in parole semplici
Measles mumps rubella and varicella vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and blunts the immune response.
Cosa fare
Avoid during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Prednisolone
- Bcg vaccine live + Prednisolone Controindicata
- Measles mumps and rubella vaccine live + Prednisolone Controindicata
- Measles vaccine + Prednisolone Controindicata
- Mifepristone + Prednisolone Controindicata
- Prednisolone + Radium-223 dichloride Controindicata
- Prednisolone + Rubella vaccine Controindicata
Domande frequenti
Can I take Measles mumps rubella and varicella vaccine live with Prednisolone?
MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Prednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine can cause disseminated vaccine-strain infection, including varicella, in patients on immunosuppressive doses of prednisolone. The immune response is also reduced.
How serious is the interaction between Measles mumps rubella and varicella vaccine live and Prednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during high-dose steroid therapy and for about one month after stopping, per local guidance. Low-dose or short-course steroids may be acceptable under specialist advice.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles vaccine. The full list is on the Prednisolone page.
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