Interazioni tra farmaci
Bcg vaccine live + Upadacitinib
Gravità: Controindicata
Bcg vaccine live and Upadacitinib: contraindicated interaction.
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Sintesi
Upadacitinib-induced immunosuppression raises the risk of disseminated BCG infection after a live BCG vaccine. The vaccine response may also be reduced.
Cosa significa questa interazione in parole semplici
Bcg vaccine live and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Immunosuppression impairs control of live attenuated mycobacteria.
Cosa fare
Avoid live BCG vaccination during upadacitinib treatment. Complete needed vaccination before starting therapy, allowing at least 4 weeks.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Upadacitinib
- Abrocitinib + Upadacitinib Controindicata
- Adenovirus types 4 and 7 live + Upadacitinib Controindicata
- Baricitinib + Upadacitinib Controindicata
- Cyclosporine + Upadacitinib Controindicata
- Dengue vaccine + Upadacitinib Controindicata
- Influenza virus vaccine quadrivalent intranasal + Upadacitinib Controindicata
Domande frequenti
Can I take Bcg vaccine live with Upadacitinib?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Upadacitinib-induced immunosuppression raises the risk of disseminated BCG infection after a live BCG vaccine. The vaccine response may also be reduced.
How serious is the interaction between Bcg vaccine live and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG vaccination during upadacitinib treatment. Complete needed vaccination before starting therapy, allowing at least 4 weeks.
What other medicines interact with Upadacitinib?
MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.
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