Interazioni tra farmaci
Dengue vaccine + Upadacitinib
Gravità: Controindicata
Dengue vaccine and Upadacitinib: contraindicated interaction.
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Sintesi
The dengue vaccine is live attenuated, and immunosuppression from upadacitinib may allow uncontrolled vaccine virus replication. The immune response may also be inadequate.
Cosa significa questa interazione in parole semplici
Dengue vaccine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Immunosuppression impairs control of live attenuated virus and reduces vaccine response.
Cosa fare
Avoid the live dengue vaccine during upadacitinib treatment. Vaccinate before starting therapy where indicated.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Upadacitinib
- Abrocitinib + Upadacitinib Controindicata
- Adenovirus types 4 and 7 live + Upadacitinib Controindicata
- Baricitinib + Upadacitinib Controindicata
- Bcg vaccine live + Upadacitinib Controindicata
- Cyclosporine + Upadacitinib Controindicata
- Influenza virus vaccine quadrivalent intranasal + Upadacitinib Controindicata
Domande frequenti
Can I take Dengue vaccine with Upadacitinib?
MediHelp rates the interaction as contraindicated. Dengue vaccine and Upadacitinib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The dengue vaccine is live attenuated, and immunosuppression from upadacitinib may allow uncontrolled vaccine virus replication. The immune response may also be inadequate.
How serious is the interaction between Dengue vaccine and Upadacitinib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live dengue vaccine during upadacitinib treatment. Vaccinate before starting therapy where indicated.
What other medicines interact with Upadacitinib?
MediHelp also lists interactions of Upadacitinib with, for example, Abrocitinib, Adenovirus types 4 and 7 live, Baricitinib. The full list is on the Upadacitinib page.
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