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Interazioni tra farmaci

Carbonyl iron + Delafloxacin

Gravità: Moderata

Carbonyl iron and Delafloxacin: moderate interaction.

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Sintesi

Iron binds oral delafloxacin in the gut and markedly reduces its absorption. This can lead to subtherapeutic antibiotic levels and treatment failure.

Cosa significa questa interazione in parole semplici

Carbonyl iron and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Carbonyl iron belongs to Miscellaneous; Delafloxacin belongs to Anti Bacterial.

Livello di evidenza: High

Perché avviene

Chelation of delafloxacin by iron cations in the gastrointestinal tract.

Cosa fare

Give oral delafloxacin at least 2 hours before or 6 hours after iron products.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Carbonyl iron with Delafloxacin?

MediHelp rates the interaction as moderate. Carbonyl iron and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds oral delafloxacin in the gut and markedly reduces its absorption. This can lead to subtherapeutic antibiotic levels and treatment failure.

How serious is the interaction between Carbonyl iron and Delafloxacin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after iron products.

What other medicines interact with Carbonyl iron?

MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.

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