Drug interactions
Carbonyl iron + Delafloxacin
Severity: Moderate
Carbonyl iron and Delafloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron binds oral delafloxacin in the gut and markedly reduces its absorption. This can lead to subtherapeutic antibiotic levels and treatment failure.
What this interaction means in plain words
Carbonyl iron and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Delafloxacin belongs to Anti Bacterial.
Why it happens
Chelation of delafloxacin by iron cations in the gastrointestinal tract.
What to do
Give oral delafloxacin at least 2 hours before or 6 hours after iron products.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderate
- Baloxavir marboxil + Carbonyl iron Moderate
- Calcium acetate + Carbonyl iron Moderate
- Calcium carbonate + Carbonyl iron Moderate
- Calcium + Carbonyl iron Moderate
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderate
Other interactions of Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderate
- Calcium carbonate + Delafloxacin Moderate
- Calcium + Delafloxacin Moderate
- Delafloxacin + Didanosine Moderate
- Delafloxacin + Ferrous fumarate Moderate
- Delafloxacin + Ferrous gluconate Moderate
Frequently asked questions
Can I take Carbonyl iron with Delafloxacin?
MediHelp rates the interaction as moderate. Carbonyl iron and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds oral delafloxacin in the gut and markedly reduces its absorption. This can lead to subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Carbonyl iron and Delafloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after iron products.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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