Interazioni tra farmaci
Delafloxacin + Didanosine
Gravità: Moderata
Delafloxacin and Didanosine: moderate interaction.
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Sintesi
Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.
Cosa significa questa interazione in parole semplici
Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Didanosine belongs to Anti Virals.
Perché avviene
Chelation of delafloxacin by the polyvalent cations in buffered didanosine reduces absorption.
Cosa fare
Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderata
- Calcium carbonate + Delafloxacin Moderata
- Calcium + Delafloxacin Moderata
- Carbonyl iron + Delafloxacin Moderata
- Delafloxacin + Ferrous fumarate Moderata
- Delafloxacin + Ferrous gluconate Moderata
Altre interazioni di Didanosine
- Didanosine + Elvitegravir / cobicistat / emtricitabine / tenofovir df Controindicata
- Didanosine + Hydroxycarbamide Controindicata
- Didanosine + Hydroxyurea Controindicata
- Didanosine + Ribavirin Controindicata
- Didanosine + Stavudine Controindicata
- Allopurinol + Didanosine Maggiore
Domande frequenti
Can I take Delafloxacin with Didanosine?
MediHelp rates the interaction as moderate. Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.
How serious is the interaction between Delafloxacin and Didanosine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.
What other medicines interact with Delafloxacin?
MediHelp also lists interactions of Delafloxacin with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Delafloxacin page.
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