Interazioni tra farmaci
Cefaclor + Warfarin
Gravità: Moderata
Cefaclor and Warfarin: moderate interaction.
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Sintesi
Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.
Cosa significa questa interazione in parole semplici
Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefaclor belongs to Anti Bacterial; Warfarin belongs to Cardiovascular.
Perché avviene
Not firmly established; possibly reduced gut-derived vitamin K or other effects on warfarin response.
Cosa fare
Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefaclor
- Bcg vaccine live + Cefaclor Moderata
- Cefaclor + Cholera vaccine Moderata
- Cefaclor + Kanamycin Moderata
- Cefaclor + Microbiota Moderata
- Cefaclor + Plazomicin Moderata
- Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderata
Altre interazioni di Warfarin
- Defibrotide + Warfarin Controindicata
- Ketorolac + Warfarin Controindicata
- Abciximab + Warfarin Maggiore
- Acetylsalicylic acid + Warfarin Maggiore
- Adagrasib + Warfarin Maggiore
- Amiodarone + Warfarin Maggiore
Domande frequenti
Can I take Cefaclor with Warfarin?
MediHelp rates the interaction as moderate. Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.
How serious is the interaction between Cefaclor and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
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