Interazioni tra farmaci
Cefixime + Microbiota
Gravità: Moderata
Cefixime and Microbiota: moderate interaction.
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Sintesi
Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
Cosa significa questa interazione in parole semplici
Cefixime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Perché avviene
Antibacterial activity against the live bacterial components of the product reduces colonization (pharmacodynamic antagonism).
Cosa fare
Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Cefixime
- Cefixime + Typhoid vaccine live Maggiore
- Cefixime + Cholera vaccine Moderata
- Cefixime + Kanamycin Moderata
- Cefixime + Plazomicin Moderata
- Cefixime + Sodium picosulfate / magnesium oxide / anhydrous citric acid Moderata
- Cefixime + Warfarin Moderata
Domande frequenti
Can I take Cefixime with Microbiota?
MediHelp rates the interaction as moderate. Cefixime and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.
How serious is the interaction between Cefixime and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.
What other medicines interact with Cefixime?
MediHelp also lists interactions of Cefixime with, for example, Typhoid vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefixime page.
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