Interazioni tra farmaci
Charcoal + Theophylline
Gravità: Moderata
Charcoal and Theophylline: moderate interaction.
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Sintesi
Activated charcoal binds theophylline in the gut and increases its elimination, including from the circulation with repeated doses. This reduces bronchodilator effect at therapeutic doses but is valuable in theophylline overdose.
Cosa significa questa interazione in parole semplici
Charcoal and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Charcoal belongs to Gastrointestinal Tract; Theophylline belongs to Respiratory.
Perché avviene
Charcoal adsorbs theophylline in the gut and enhances its elimination by gastrointestinal dialysis.
Cosa fare
Avoid concurrent charcoal during therapeutic theophylline use or separate doses by several hours. In overdose, give repeated-dose charcoal and monitor serum theophylline levels.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Charcoal
- Charcoal + Citalopram Moderata
- Charcoal + Digoxin Moderata
- Charcoal + Leflunomide Moderata
- Charcoal + Methotrexate Moderata
- Charcoal + Tiratricol Moderata
- Acarbose + Charcoal Minore
Altre interazioni di Theophylline
- Riociguat + Theophylline Controindicata
- Adenosine + Theophylline Maggiore
- Apalutamide + Theophylline Maggiore
- Bupropion + Theophylline Maggiore
- Carvedilol + Theophylline Maggiore
- Cimetidine + Theophylline Maggiore
Domande frequenti
Can I take Charcoal with Theophylline?
MediHelp rates the interaction as moderate. Charcoal and Theophylline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Activated charcoal binds theophylline in the gut and increases its elimination, including from the circulation with repeated doses. This reduces bronchodilator effect at therapeutic doses but is valuable in theophylline overdose.
How serious is the interaction between Charcoal and Theophylline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent charcoal during therapeutic theophylline use or separate doses by several hours. In overdose, give repeated-dose charcoal and monitor serum theophylline levels.
What other medicines interact with Charcoal?
MediHelp also lists interactions of Charcoal with, for example, Citalopram, Digoxin, Leflunomide. The full list is on the Charcoal page.
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