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Interazioni tra farmaci

Cimetidine + Vitamin B12

Gravità: Minore

Cimetidine and Vitamin B12: minor interaction.

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Sintesi

Cimetidine reduces gastric acid, which lowers release of B12 from food proteins and may lower absorption with long-term use. Absorption of crystalline oral B12 is less affected, so clinical deficiency is uncommon.

Cosa significa questa interazione in parole semplici

Cimetidine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cimetidine belongs to Gastrointestinal Tract; Vitamin B12 belongs to Gastrointestinal Tract.

Livello di evidenza: Moderate

Perché avviene

Reduced gastric acid secretion impairs liberation of protein-bound dietary B12.

Cosa fare

Monitor B12 status in long-term users, especially older adults or those with other risk factors. Supplement if levels are low.

Cosa chiedere al farmacista

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Cimetidine with Vitamin B12?

MediHelp rates the interaction as minor. Cimetidine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cimetidine reduces gastric acid, which lowers release of B12 from food proteins and may lower absorption with long-term use. Absorption of crystalline oral B12 is less affected, so clinical deficiency is uncommon.

How serious is the interaction between Cimetidine and Vitamin B12?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor B12 status in long-term users, especially older adults or those with other risk factors. Supplement if levels are low.

What other medicines interact with Vitamin B12?

MediHelp also lists interactions of Vitamin B12 with, for example, Chloramphenicol, Dichlorphenamide, Metformin. The full list is on the Vitamin B12 page.

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