Interazioni tra farmaci
Dasatinib + Thioridazine
Gravità: Controindicata
Dasatinib and Thioridazine: contraindicated interaction.
Ultimo aggiornamento
Per operatori sanitari — solo a scopo di riferimento. Questa pagina è una sintesi breve, non è un parere medico e non sostituisce il RCP ufficiale né il giudizio clinico. Verificare sempre prima di prescrivere o dispensare.
Il contenuto clinico di questa pagina è disponibile solo in inglese.
Sintesi
Thioridazine has a marked QT-prolonging effect and dasatinib can also prolong the QT interval. Together they substantially raise the risk of torsades de pointes and sudden cardiac death.
Cosa significa questa interazione in parole semplici
Dasatinib and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dasatinib belongs to Oncology; Thioridazine belongs to Central Nervous System.
Perché avviene
Additive prolongation of cardiac repolarization through potassium channel effects.
Cosa fare
Avoid the combination and choose an antipsychotic with lower QT risk. If dasatinib is essential, do not use thioridazine.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Per gli utenti Pro+
Sblocca la pagina completa
Crei un account e avvii una prova di Pro+ per sbloccare le indicazioni complete sulla gestione di Dasatinib e Thioridazine, le note aggiuntive, il dettaglio delle evidenze e il controllo delle interazioni per un'intera prescrizione.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Provi Pro+ gratis per 14 giorni sul web. Nessuna carta.
Altre interazioni di Thioridazine
- Abiraterone + Thioridazine Controindicata
- Adagrasib + Thioridazine Controindicata
- Amiodarone + Thioridazine Controindicata
- Amisulpride + Thioridazine Controindicata
- Amitriptyline + Thioridazine Controindicata
- Amoxapine + Thioridazine Controindicata
Altre interazioni di Dasatinib
- Dasatinib + Saquinavir Controindicata
- Adagrasib + Dasatinib Maggiore
- Amiodarone + Dasatinib Maggiore
- Amisulpride + Dasatinib Maggiore
- Amitriptyline + Dasatinib Maggiore
- Amobarbital + Dasatinib Maggiore
Domande frequenti
Can I take Dasatinib with Thioridazine?
MediHelp rates the interaction as contraindicated. Dasatinib and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Thioridazine has a marked QT-prolonging effect and dasatinib can also prolong the QT interval. Together they substantially raise the risk of torsades de pointes and sudden cardiac death.
How serious is the interaction between Dasatinib and Thioridazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose an antipsychotic with lower QT risk. If dasatinib is essential, do not use thioridazine.
What other medicines interact with Thioridazine?
MediHelp also lists interactions of Thioridazine with, for example, Abiraterone, Adagrasib, Amiodarone. The full list is on the Thioridazine page.
Monografie complete, posologie e verifica delle interazioni nell'app MediHelp
Apra il riferimento completo, verifichi le interazioni tra più farmaci e usi gli strumenti di posologia nell'app MediHelp.
