Interazioni tra farmaci
Deflazacort + Penicillin g
Gravità: Moderata
Deflazacort and Penicillin g: moderate interaction.
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Sintesi
High-dose penicillin G can cause hypokalemia through delivery of a nonreabsorbable anion to the distal nephron, which increases potassium loss. Deflazacort, a corticosteroid, has mineralocorticoid activity that can also lower potassium, so the effects may add together.
Cosa significa questa interazione in parole semplici
Deflazacort and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Penicillin g belongs to Anti Bacterial.
Perché avviene
Additive renal potassium wasting from penicillin G and corticosteroid mineralocorticoid effect.
Cosa fare
Monitor serum potassium during high-dose penicillin G therapy with deflazacort and replace potassium as needed.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Penicillin g
- Amifampridine + Penicillin g Moderata
- Amiloride + Penicillin g Moderata
- Bcg vaccine live + Penicillin g Moderata
- Cholera vaccine + Penicillin g Moderata
- Colestipol + Penicillin g Moderata
- Demeclocycline + Penicillin g Moderata
Altre interazioni di Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Controindicata
- Bcg vaccine live + Deflazacort Controindicata
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Controindicata
- Deflazacort + Measles mumps and rubella vaccine Controindicata
- Deflazacort + Measles mumps and rubella vaccine live Controindicata
- Deflazacort + Measles mumps rubella and varicella vaccine live Controindicata
Domande frequenti
Can I take Deflazacort with Penicillin g?
MediHelp rates the interaction as moderate. Deflazacort and Penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. High-dose penicillin G can cause hypokalemia through delivery of a nonreabsorbable anion to the distal nephron, which increases potassium loss. Deflazacort, a corticosteroid, has mineralocorticoid activity that can also lower potassium, so the effects may add together.
How serious is the interaction between Deflazacort and Penicillin g?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium during high-dose penicillin G therapy with deflazacort and replace potassium as needed.
What other medicines interact with Penicillin g?
MediHelp also lists interactions of Penicillin g with, for example, Amifampridine, Amiloride, Bcg vaccine live. The full list is on the Penicillin g page.
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