Interazioni tra farmaci
Dicloxacillin + Isavuconazonium
Gravità: Moderata
Dicloxacillin and Isavuconazonium: moderate interaction.
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Sintesi
Dicloxacillin is a CYP3A4 inducer and may lower exposure to isavuconazole, the active moiety of isavuconazonium. Reduced antifungal concentrations could compromise treatment of invasive fungal infection.
Cosa significa questa interazione in parole semplici
Dicloxacillin and Isavuconazonium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicloxacillin belongs to Anti Bacterial; Isavuconazonium belongs to Anti Fungals.
Perché avviene
Induction of CYP3A4 by dicloxacillin increases isavuconazole metabolism.
Cosa fare
Monitor clinical response to antifungal therapy and consider isavuconazole trough levels if available; choose an alternative antibacterial if feasible.
Cosa chiedere al farmacista
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Altre interazioni di Dicloxacillin
- Dicloxacillin + Phenindione Maggiore
- Atogepant + Dicloxacillin Moderata
- Axitinib + Dicloxacillin Moderata
- Bcg vaccine live + Dicloxacillin Moderata
- Cholera vaccine + Dicloxacillin Moderata
- Demeclocycline + Dicloxacillin Moderata
Altre interazioni di Isavuconazonium
- Amobarbital + Isavuconazonium Controindicata
- Apalutamide + Isavuconazonium Controindicata
- Carbamazepine + Isavuconazonium Controindicata
- Cisapride + Isavuconazonium Controindicata
- Efavirenz + Isavuconazonium Controindicata
- Enzalutamide + Isavuconazonium Controindicata
Domande frequenti
Can I take Dicloxacillin with Isavuconazonium?
MediHelp rates the interaction as moderate. Dicloxacillin and Isavuconazonium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dicloxacillin is a CYP3A4 inducer and may lower exposure to isavuconazole, the active moiety of isavuconazonium. Reduced antifungal concentrations could compromise treatment of invasive fungal infection.
How serious is the interaction between Dicloxacillin and Isavuconazonium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor clinical response to antifungal therapy and consider isavuconazole trough levels if available; choose an alternative antibacterial if feasible.
What other medicines interact with Dicloxacillin?
MediHelp also lists interactions of Dicloxacillin with, for example, Phenindione, Atogepant, Axitinib. The full list is on the Dicloxacillin page.
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