Interazioni tra farmaci
Diflunisal + Ketorolac
Gravità: Controindicata
Diflunisal and Ketorolac: contraindicated interaction.
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Sintesi
Ketorolac is contraindicated with other NSAIDs, and diflunisal is an NSAID. Combined use increases the risk of gastrointestinal bleeding and ulceration, renal injury and platelet dysfunction without added analgesia.
Cosa significa questa interazione in parole semplici
Diflunisal and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Diflunisal belongs to Musculoskeletal; Ketorolac belongs to Musculoskeletal.
Perché avviene
Additive NSAID toxicity (GI, renal, antiplatelet)
Cosa fare
Do not use two NSAIDs together; give ketorolac as the sole NSAID and for no longer than 5 days.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Diflunisal
- Diflunisal + Ketorolac intranasal Controindicata
- Acemetacin + Diflunisal Maggiore
- Acetazolamide + Diflunisal Maggiore
- Alteplase + Diflunisal Maggiore
- Amiloride + Diflunisal Maggiore
- Amlodipine-hydrochlorothiazide-valsartan + Diflunisal Maggiore
Altre interazioni di Ketorolac
- Aceclofenac + Ketorolac Controindicata
- Acemetacin + Ketorolac Controindicata
- Acetylsalicylic acid + Ketorolac Controindicata
- Apixaban + Ketorolac Controindicata
- Argatroban + Ketorolac Controindicata
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Controindicata
Domande frequenti
Can I take Diflunisal with Ketorolac?
MediHelp rates the interaction as contraindicated. Diflunisal and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac is contraindicated with other NSAIDs, and diflunisal is an NSAID. Combined use increases the risk of gastrointestinal bleeding and ulceration, renal injury and platelet dysfunction without added analgesia.
How serious is the interaction between Diflunisal and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use two NSAIDs together; give ketorolac as the sole NSAID and for no longer than 5 days.
What other medicines interact with Diflunisal?
MediHelp also lists interactions of Diflunisal with, for example, Ketorolac intranasal, Acemetacin, Acetazolamide. The full list is on the Diflunisal page.
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