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Interazioni tra farmaci

Eletriptan + Naratriptan

Gravità: Controindicata

Eletriptan and Naratriptan: contraindicated interaction.

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Sintesi

Eletriptan and naratriptan are both 5-HT1B/1D agonists that constrict cranial and coronary arteries. Used within a day of each other their vasoconstriction is additive, with risk of coronary spasm and raised blood pressure.

Cosa significa questa interazione in parole semplici

Eletriptan and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Eletriptan belongs to Central Nervous System; Naratriptan belongs to Central Nervous System.

Livello di evidenza: High

Perché avviene

Additive 5-HT1B/1D-mediated vasoconstriction

Cosa fare

Do not use two triptans within 24 hours; limit each attack to one triptan.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Eletriptan with Naratriptan?

MediHelp rates the interaction as contraindicated. Eletriptan and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Eletriptan and naratriptan are both 5-HT1B/1D agonists that constrict cranial and coronary arteries. Used within a day of each other their vasoconstriction is additive, with risk of coronary spasm and raised blood pressure.

How serious is the interaction between Eletriptan and Naratriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use two triptans within 24 hours; limit each attack to one triptan.

What other medicines interact with Naratriptan?

MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Naratriptan page.

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