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Ergoloid mesylates + Naratriptan

Gravità: Controindicata

Ergoloid mesylates and Naratriptan: contraindicated interaction.

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Sintesi

Both drugs act on serotonergic and vascular receptors, so additive vasoconstriction is possible. Ergoloid's vasoconstrictor activity is modest, but triptan labeling cautions against ergot-type drugs.

Cosa significa questa interazione in parole semplici

Ergoloid mesylates and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Livello di evidenza: Low

Perché avviene

Additive vasoconstriction through serotonin receptor agonism and ergot-derived receptor effects.

Cosa fare

Avoid use together and separate by at least 24 hours. Reconsider the need for ergoloid in patients with migraine.

Cosa chiedere al farmacista

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Ergoloid mesylates with Naratriptan?

MediHelp rates the interaction as contraindicated. Ergoloid mesylates and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs act on serotonergic and vascular receptors, so additive vasoconstriction is possible. Ergoloid's vasoconstrictor activity is modest, but triptan labeling cautions against ergot-type drugs.

How serious is the interaction between Ergoloid mesylates and Naratriptan?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid use together and separate by at least 24 hours. Reconsider the need for ergoloid in patients with migraine.

What other medicines interact with Naratriptan?

MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Naratriptan page.

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