Interazioni tra farmaci
Enoxaparin + Ketorolac
Gravità: Controindicata
Enoxaparin and Ketorolac: contraindicated interaction.
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Sintesi
Ketorolac inhibits platelets and can cause GI bleeding, and enoxaparin is an anticoagulant, so serious hemorrhage including spinal or epidural hematoma is more likely. Ketorolac labeling contraindicates use in patients at risk of bleeding.
Cosa significa questa interazione in parole semplici
Enoxaparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Enoxaparin belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
Perché avviene
Additive hemostatic impairment through antiplatelet NSAID effect and low molecular weight heparin anti-Xa activity.
Cosa fare
Avoid ketorolac in patients receiving enoxaparin and choose a non-NSAID analgesic; if exposure occurs, monitor for bleeding and neurologic signs after neuraxial procedures.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Ketorolac
- Aceclofenac + Ketorolac Controindicata
- Acemetacin + Ketorolac Controindicata
- Acetylsalicylic acid + Ketorolac Controindicata
- Apixaban + Ketorolac Controindicata
- Argatroban + Ketorolac Controindicata
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Controindicata
Altre interazioni di Enoxaparin
- Defibrotide + Enoxaparin Controindicata
- Enoxaparin + Mifepristone Controindicata
- Abciximab + Enoxaparin Maggiore
- Aceclofenac + Enoxaparin Maggiore
- Acetylsalicylic acid + Enoxaparin Maggiore
- Alteplase + Enoxaparin Maggiore
Domande frequenti
Can I take Enoxaparin with Ketorolac?
MediHelp rates the interaction as contraindicated. Enoxaparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac inhibits platelets and can cause GI bleeding, and enoxaparin is an anticoagulant, so serious hemorrhage including spinal or epidural hematoma is more likely. Ketorolac labeling contraindicates use in patients at risk of bleeding.
How serious is the interaction between Enoxaparin and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac in patients receiving enoxaparin and choose a non-NSAID analgesic; if exposure occurs, monitor for bleeding and neurologic signs after neuraxial procedures.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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