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Interazioni tra farmaci

Iron + Roxadustat

Gravità: Moderata

Iron and Roxadustat: moderate interaction.

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Sintesi

Oral iron can bind roxadustat in the gut and reduce its absorption. This may lower roxadustat exposure and its effect on hemoglobin.

Cosa significa questa interazione in parole semplici

Iron and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Iron belongs to Gastrointestinal Tract; Roxadustat belongs to Miscellaneous.

Livello di evidenza: Moderate

Perché avviene

Chelation of roxadustat by iron cations in the gastrointestinal tract, reducing absorption.

Cosa fare

Take roxadustat at least 1 hour after oral iron products. Monitor hemoglobin and iron indices.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Iron with Roxadustat?

MediHelp rates the interaction as moderate. Iron and Roxadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron can bind roxadustat in the gut and reduce its absorption. This may lower roxadustat exposure and its effect on hemoglobin.

How serious is the interaction between Iron and Roxadustat?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take roxadustat at least 1 hour after oral iron products. Monitor hemoglobin and iron indices.

What other medicines interact with Roxadustat?

MediHelp also lists interactions of Roxadustat with, for example, Gemfibrozil, Probenecid, Atorvastatin. The full list is on the Roxadustat page.

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