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Interazioni tra farmaci

Lycopus + Propylthiouracil

Gravità: Moderata

Lycopus and Propylthiouracil: moderate interaction.

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Sintesi

Lycopus (bugleweed) has antithyroid activity and may add to the effect of propylthiouracil, increasing the risk of hypothyroidism. Evidence is limited to traditional use and small studies.

Cosa significa questa interazione in parole semplici

Lycopus and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Livello di evidenza: Low

Perché avviene

Additive antithyroid effect through reduced thyroid stimulation and peripheral T4 to T3 conversion.

Cosa fare

Avoid combining the herb with antithyroid drugs unless supervised. Monitor TSH and free T4 if both are used.

Cosa chiedere al farmacista

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Domande frequenti

Can I take Lycopus with Propylthiouracil?

MediHelp rates the interaction as moderate. Lycopus and Propylthiouracil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lycopus (bugleweed) has antithyroid activity and may add to the effect of propylthiouracil, increasing the risk of hypothyroidism. Evidence is limited to traditional use and small studies.

How serious is the interaction between Lycopus and Propylthiouracil?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining the herb with antithyroid drugs unless supervised. Monitor TSH and free T4 if both are used.

What other medicines interact with Propylthiouracil?

MediHelp also lists interactions of Propylthiouracil with, for example, Carbamazepine, Clozapine, Methimazole. The full list is on the Propylthiouracil page.

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