Interazioni tra farmaci
Measles mumps and rubella vaccine + Melphalan
Gravità: Controindicata
Measles mumps and rubella vaccine and Melphalan: contraindicated interaction.
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Sintesi
Melphalan causes marked myelosuppression and immunosuppression, so live attenuated vaccine viruses may replicate unchecked and cause disseminated infection. Vaccine efficacy is also reduced.
Cosa significa questa interazione in parole semplici
Measles mumps and rubella vaccine and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Measles mumps and rubella vaccine belongs to Miscellaneous; Melphalan belongs to Oncology.
Perché avviene
Cytotoxic immunosuppression permits uncontrolled replication of live attenuated virus.
Cosa fare
Avoid live vaccines during melphalan therapy; give them only after immune recovery, usually at least 3 months after stopping.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Controindicata
- Anakinra + Measles mumps and rubella vaccine Controindicata
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Controindicata
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Controindicata
- Azathioprine + Measles mumps and rubella vaccine Controindicata
- Basiliximab + Measles mumps and rubella vaccine Controindicata
Altre interazioni di Melphalan
- Adenovirus types 4 and 7 live + Melphalan Controindicata
- Bcg vaccine live + Melphalan Controindicata
- Influenza virus vaccine quadrivalent intranasal + Melphalan Controindicata
- Measles mumps and rubella vaccine live + Melphalan Controindicata
- Measles mumps rubella and varicella vaccine live + Melphalan Controindicata
- Measles vaccine + Melphalan Controindicata
Domande frequenti
Can I take Measles mumps and rubella vaccine with Melphalan?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine and Melphalan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Melphalan causes marked myelosuppression and immunosuppression, so live attenuated vaccine viruses may replicate unchecked and cause disseminated infection. Vaccine efficacy is also reduced.
How serious is the interaction between Measles mumps and rubella vaccine and Melphalan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during melphalan therapy; give them only after immune recovery, usually at least 3 months after stopping.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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