Interazioni tra farmaci
Methylergonovine + Naratriptan
Gravità: Controindicata
Methylergonovine and Naratriptan: contraindicated interaction.
Ultimo aggiornamento
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Sintesi
Methylergonovine is a potent vasoconstrictor, and naratriptan adds further vasoconstriction. Prolonged vasospasm and ischemia may follow.
Cosa significa questa interazione in parole semplici
Methylergonovine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Perché avviene
Additive vasoconstriction via 5-HT1B/1D agonism and ergot adrenergic and serotonergic effects.
Cosa fare
Do not give together; separate by at least 24 hours. Use a non-ergot uterotonic if bleeding control is needed.
Cosa chiedere al farmacista
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Altre interazioni di Naratriptan
- Almotriptan + Naratriptan Controindicata
- Dihydroergotamine intranasal + Naratriptan Controindicata
- Dihydroergotamine + Naratriptan Controindicata
- Eletriptan + Naratriptan Controindicata
- Ergoloid mesylates + Naratriptan Controindicata
- Ergotamine + Naratriptan Controindicata
Domande frequenti
Can I take Methylergonovine with Naratriptan?
MediHelp rates the interaction as contraindicated. Methylergonovine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylergonovine is a potent vasoconstrictor, and naratriptan adds further vasoconstriction. Prolonged vasospasm and ischemia may follow.
How serious is the interaction between Methylergonovine and Naratriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give together; separate by at least 24 hours. Use a non-ergot uterotonic if bleeding control is needed.
What other medicines interact with Naratriptan?
MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Naratriptan page.
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