医薬品リファレンス
Articaine
Articaine is a medicine in the class central nervous system.
- 薬効分類: Central Nervous System
最終更新日 出典: US FDA label
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Central Nervous System
- 既知の相互作用
- 3 (中等度: 3)
作用のしくみ
Articaine HCl is an amide local anesthetic. Local anesthetics block the generation and conduction of nerve impulses, presumably by raising the threshold for electrical excitation, slowing impulse propagation and reducing the rate of rise of the action potential.
成人の通常用量（添付文書の要約）
Dental local anaesthesia by submucosal infiltration: 0.5 to 2.5 mL of a 4% (40 mg/mL) solution (20 to 100 mg articaine hydrochloride), injected slowly.
妊娠と授乳
- 妊娠
- Safe Dental local anaesthetic (usually with adrenaline); widely used in pregnancy without evidence of harm. Needed dental treatment should not be delayed; elective work is best done in the 2nd trimester.
- 授乳
- Safe Short-acting and poorly absorbed by the infant; amounts in milk after dental use are small. Breastfeeding can continue after a dental procedure.
報告されている副作用
- Persistent paresthesias of lips, tongue and oral tissues
- Hypoesthesia
注意が必要な方
- Persistent paresthesias of the lips, tongue and oral tissues have been reported with articaine hydrochloride, with slow, incomplete or no recovery, chiefly after mandibular nerve blocks.
- Hypoesthesia has been reported with articaine, especially in pediatric age groups; prolonged numbness can lead to soft tissue injuries of the lips and tongue.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (3)
- Articaine + Nadolol Moderate
- Articaine + Propranolol Moderate
- Articaine + Timolol Moderate
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Articaineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Pharmacokinetics
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同じ分類のほかの薬剤
よくある質問
What is Articaine used for?
Articaine is a medicine in the class central nervous system.
What side effects have been reported with Articaine?
Persistent paresthesias of lips, tongue and oral tissues, Hypoesthesia.
Can Articaine be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Dental local anaesthetic (usually with adrenaline); widely used in pregnancy without evidence of harm. Needed dental treatment should not be delayed; elective work is best done in the 2nd trimester. Breastfeeding: Safe. Short-acting and poorly absorbed by the infant; amounts in milk after dental use are small. Breastfeeding can continue after a dental procedure.
What does Articaine interact with?
MediHelp lists 3 known interactions for Articaine. Moderate: 3. The most serious include Nadolol, Propranolol, Timolol.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
