医薬品リファレンス
Clemastine
Clemastine is a medicine in the class respiratory. It is used for allergic rhinitis.
- 薬効分類: Respiratory
- 効能・効果: allergic rhinitis
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Respiratory
- 一般的な剤形
- 錠剤, シロップ剤, 注射剤
- 一般的な規格
- 1 mg, 0.67 mg/5 ml, 1 mg/10 ml
- 既知の相互作用
- 230 (重大: 19 · 中等度: 170 · 軽度: 41)
- 商品名
- 6
- 国・市場
- 2
何に使われるか
作用のしくみ
Clemastine competes with histamine for the histamine H1 receptor, reversible competitive inhibitor.
成人の通常用量（添付文書の要約）
Allergic Rhinitis 1.34 mg PO q12hr; not to exceed 8.04 mg/day for syrup or 2.68 mg/24 hours for tablets
妊娠と授乳
- 妊娠
- Unknown Limited human data with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine have more pregnancy data and are preferred.
- 授乳
- Safe US label: do not use while nursing (antihistamines carry higher risk for infants). One 10-week-old had drowsiness, irritability, poor feeding and high-pitched crying (mother also on two antiseizure drugs). LactMed: small occasional or single bedtime doses are acceptable; prefer a non-sedating drug.
報告されている副作用
- Fatigue
- Sedation
- Headaches
- Dry Mouth
禁忌
- Documented hypersensitivity
- Lower respiratory disease, eg, asthma (controversial)
- Preemies & neonates
注意が必要な方
- Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely.
- Older adults may be more sensitive to the side effects of this drug, especially drowsiness, constipation, problems urinating, or confusion.
- Liquid preparations of this product may contain sugar and/or alcohol. Caution is advised if you have diabetes.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (230)
- Alfentanil + Clemastine Major
- Benzhydrocodone / acetaminophen + Clemastine Major
- Buprenorphine buccal + Clemastine Major
- Buprenorphine long-acting + Clemastine Major
- Buprenorphine subdermal implant + Clemastine Major
- Buprenorphine transdermal + Clemastine Major
- Calcium / magnesium / potassium / sodium oxybates + Clemastine Major
- Clemastine + Dextromoramide Major
- Clemastine + Diamorphine Major
- Clemastine + Fentanyl intranasal Major
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Clemastineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
WebでPro+を14日間無料でお試し。カード登録不要。
同じ分類のほかの薬剤
よくある質問
What is Clemastine used for?
Clemastine is a medicine in the class respiratory. It is used for Allergic rhinitis, Insect bites, Pruritus.
What side effects have been reported with Clemastine?
Fatigue, Sedation, Headaches, Dry Mouth.
Can Clemastine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Limited human data with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine have more pregnancy data and are preferred. Breastfeeding: Safe. US label: do not use while nursing (antihistamines carry higher risk for infants). One 10-week-old had drowsiness, irritability, poor feeding and high-pitched crying (mother also on two antiseizure drugs). LactMed: small occasional or single bedtime doses are acceptable; prefer a non-sedating drug.
What does Clemastine interact with?
MediHelp lists 230 known interactions for Clemastine. Major: 19 · Moderate: 170 · Minor: 41. The most serious include Alfentanil, Benzhydrocodone / acetaminophen, Buprenorphine buccal.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
