医薬品リファレンス
Dihydrotachysterol
Dihydrotachysterol is a medicine in the class musculoskeletal. It is used for hypocalcemia.
- 薬効分類: Musculoskeletal
- 効能・効果: hypocalcemia
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Musculoskeletal
何に使われるか
作用のしくみ
Dihydrotachysterol is effective in the elevation of serum calcium by stimulating intestinal calcium absorption and mobilizing bone calcium in the absence of parathyroid hormone and of functioning renal tissue. Dihydrotachysterol also increases renal phosphate excretion.
成人の通常用量(添付文書の要約)
Hypocalcemia : Initial dose: 0.25 to 0.8 mg orally once a day for several days. Maintenance dose: 0.2 to 1 mg orally once a day.
妊娠と授乳
- 妊娠
- Safe Vitamin D analogue, now largely discontinued. Correct doses for hypoparathyroidism are not linked to birth defects, but overdose and high maternal calcium can harm fetal development (aorta, retina). If needed, continue with regular calcium checks.
- 授乳
- Unknown No data on milk levels; other vitamin D analogues pass into milk. Swiss label: do not breastfeed while taking it. German label: breastfeeding needs close blood calcium checks in mother and infant. If used, monitor the infant's calcium.
報告されている副作用
- Dry mouth
- Vomiting
- Nausea
- Bone pain, hard lumps under your skin
- Eyes that are more sensitive to light;
- Metallic taste in your mouth
禁忌
- Hypercalcaemia.
- Hypervitaminosis D (vitamin D toxicity).
- Abnormal sensitivity to the effects of vitamin D.
注意が必要な方
- Monitor serum calcium regularly, frequently during dose titration and periodically during maintenance, because the margin between therapeutic and toxic doses is narrow.
- Hypercalcaemia may develop. Signs include weakness, fatigue, headache, nausea, vomiting, constipation, polyuria, polydipsia and confusion. Stop treatment if hypercalcaemia occurs.
- Effects may persist for days to weeks after stopping because of prolonged action, so hypercalcaemia may not resolve immediately.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Dihydrotachysterolの完全なモノグラフ(用量、妊娠・授乳、副作用、警告、すべての相互作用)を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
WebでPro+を14日間無料でお試し。カード登録不要。
同じ分類のほかの薬剤
よくある質問
What is Dihydrotachysterol used for?
Dihydrotachysterol is a medicine in the class musculoskeletal. It is used for Hypocalcemia, Hypoparathyroidism, Hypophosphatemia, Osteoporosis, Renal osteodystrophy.
What side effects have been reported with Dihydrotachysterol?
Dry mouth, Vomiting, Nausea, Bone pain, hard lumps under your skin, Eyes that are more sensitive to light;, Metallic taste in your mouth.
Can Dihydrotachysterol be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Vitamin D analogue, now largely discontinued. Correct doses for hypoparathyroidism are not linked to birth defects, but overdose and high maternal calcium can harm fetal development (aorta, retina). If needed, continue with regular calcium checks. Breastfeeding: Unknown. No data on milk levels; other vitamin D analogues pass into milk. Swiss label: do not breastfeed while taking it. German label: breastfeeding needs close blood calcium checks in mother and infant. If used, monitor the infant's calcium.
What does Dihydrotachysterol interact with?
MediHelp does not list a checked interaction for Dihydrotachysterol yet. Always tell your pharmacist about every medicine you take.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。