医薬品リファレンス
Ixekizumab
Ixekizumab is a medicine in the class miscellaneous. It is used for ankylosing spondylitis.
- 薬効分類: Miscellaneous
- 効能・効果: ankylosing spondylitis
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Miscellaneous
- ATCコード
- L04AC13
- 一般的な剤形
- 注射剤
- 一般的な規格
- 80 mg/ml
- 既知の相互作用
- 13 (重大: 2 · 中等度: 2 · 軽度: 9)
- 商品名
- 5
- 国・市場
- 5
何に使われるか
作用のしくみ
Humanized monoclonal IgG4 antibody that targets interleukin-17A (IL-17A) and neutralizes the proinflammatory effects of IL-17A
成人の通常用量（添付文書の要約）
Psoriasis (Week 0): 160 mg SC (two 80-mg injections), THEN Weeks 2, 4, 6, 8, 10, and 12: 80 mg SC q2Weeks, THEN Week 16 and thereafter: 80 mg SC q4Weeks
妊娠と授乳
- 妊娠
- Unknown Human IgG is known to cross the placental barrier; therefore, the drug may be transmitted from the mother to the developing fetus
- 授乳
- Unknown There are no available data on presence of this drug in human milk, effects on breastfed infant, or on milk production; the drug was detected in the milk of lactating cynomolgus monkeys; when a drug is present in animal milk, it is likely that the drug will be present in human milk
報告されている副作用
- Tinea infections
- Serious infections
- Upper respiratory tract infections
- Injection site reacation
- Thrombocytopenia
- Nausea
禁忌
- Hypersensitivity reaction (eg, anaphylaxis) to drug or excipients
注意が必要な方
- Patients receiving treatment may be at increased risk of inflammatory bowel disease; in clinical trials, Crohn’s disease and ulcerative colitis, including exacerbations, occurred at a greater frequency in treated group than placebo control group; during treatment, monitor for onset or exacerbation of inflammatory bowel disease and if IBD occurs...
- ... discontinue therapy and initiate appropriate medical management
- Prior to initiating drug, consider completion of all age-appropriate immunizations; avoid use of live vaccines; no data are available on the response to live vaccines while taking ixekizumab
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (13)
- Ixekizumab + Measles mumps and rubella vaccine Major
- Ixekizumab + Upadacitinib Major
- Ifosfamide + Ixekizumab Moderate
- Ixekizumab + Lomustine Moderate
- Carbamazepine + Ixekizumab Minor
- Cyclosporin + Ixekizumab Minor
- Ethosuximide + Ixekizumab Minor
- Ixekizumab + Phenytoin Minor
- Ixekizumab + Pneumococcal vaccine 13-valent Minor
- Ixekizumab + Quinidine Minor
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Ixekizumabの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
WebでPro+を14日間無料でお試し。カード登録不要。
同じ分類のほかの薬剤
よくある質問
What is Ixekizumab used for?
Ixekizumab is a medicine in the class miscellaneous. It is used for Ankylosing spondylitis, Psoriasis, Psoriatic arthritis, Spondyloarthritis.
What side effects have been reported with Ixekizumab?
Tinea infections, Serious infections, Upper respiratory tract infections, Injection site reacation, Thrombocytopenia, Nausea.
Can Ixekizumab be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Human IgG is known to cross the placental barrier; therefore, the drug may be transmitted from the mother to the developing fetus Breastfeeding: Unknown. There are no available data on presence of this drug in human milk, effects on breastfed infant, or on milk production; the drug was detected in the milk of lactating cynomolgus monkeys; when a drug is present in animal milk, it is likely that the drug will be present in human milk
What does Ixekizumab interact with?
MediHelp lists 13 known interactions for Ixekizumab. Major: 2 · Moderate: 2 · Minor: 9. The most serious include Measles mumps and rubella vaccine, Upadacitinib, Ifosfamide.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
