相互作用
Carbamazepine + Ixekizumab
重症度: 軽度
Carbamazepine and Ixekizumab: minor interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Ixekizumab may reverse cytokine-mediated suppression of CYP450 enzymes in patients with inflammatory disease. This may alter clearance of carbamazepine, a narrow therapeutic index drug. The effect is theoretical.
この相互作用をわかりやすく説明すると
Carbamazepine and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Carbamazepine belongs to Central Nervous System; Ixekizumab belongs to Miscellaneous.
なぜ起こるのか
Normalization of cytokine-suppressed CYP450 expression may alter carbamazepine metabolism.
対処法
Consider checking carbamazepine levels when ixekizumab is started or stopped. Adjust the dose only if levels or response change.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CarbamazepineとIxekizumabの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Carbamazepineのその他の相互作用
Ixekizumabのその他の相互作用
よくある質問
Can I take Carbamazepine with Ixekizumab?
MediHelp rates the interaction as minor. Carbamazepine and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ixekizumab may reverse cytokine-mediated suppression of CYP450 enzymes in patients with inflammatory disease. This may alter clearance of carbamazepine, a narrow therapeutic index drug. The effect is theoretical.
How serious is the interaction between Carbamazepine and Ixekizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider checking carbamazepine levels when ixekizumab is started or stopped. Adjust the dose only if levels or response change.
What other medicines interact with Carbamazepine?
MediHelp also lists interactions of Carbamazepine with, for example, Artemether / lumefantrine, Cabotegravir, Delamanid. The full list is on the Carbamazepine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
