相互作用
Cyclosporin + Ixekizumab
重症度: 軽度
Cyclosporin and Ixekizumab: minor interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
この相互作用をわかりやすく説明すると
Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Ixekizumab belongs to Miscellaneous.
なぜ起こるのか
Cytokine normalization may modestly increase CYP-mediated cyclosporine metabolism; this is theoretical.
対処法
Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CyclosporinとIxekizumabの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cyclosporinのその他の相互作用
Ixekizumabのその他の相互作用
よくある質問
Can I take Cyclosporin with Ixekizumab?
MediHelp rates the interaction as minor. Cyclosporin and Ixekizumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Reduced inflammation during IL-17A blockade may restore CYP450 activity that was suppressed by cytokines, theoretically lowering cyclosporine concentrations. A clinically important effect has not been established. Combined immunosuppression also raises infection concerns.
How serious is the interaction between Cyclosporin and Ixekizumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough levels and clinical response when ixekizumab is started or stopped. Monitor for infection.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
