医薬品リファレンス
Pancuronium
Pancuronium is a medicine in the class musculoskeletal. It is used for cesarean section.
- 薬効分類: Musculoskeletal
- 効能・効果: cesarean section
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Musculoskeletal
- 一般的な剤形
- 注射剤
- 一般的な規格
- 4 mg/2 ml, 2 mg/ml, 2 mg
- 既知の相互作用
- 145 (重大: 14 · 中等度: 73 · 軽度: 58)
- 商品名
- 6
- 国・市場
- 3
何に使われるか
作用のしくみ
Non-depolarizing skeletal muscle relaxant; cholinergic receptor antagonist
成人の通常用量（添付文書の要約）
General Anesthesia Adjunct/Cesarean Section (Load): 0.04-0.1 mg/kg IV
妊娠と授乳
- 妊娠
- Safe Long-acting muscle relaxant used in anaesthesia, including caesarean section; only small amounts cross the placenta. Its effect can be prolonged by magnesium sulphate. Acceptable for anaesthesia when needed.
- 授乳
- Safe No milk data, but it is highly polar and poorly absorbed by mouth, so little is likely to reach milk or the infant (LactMed). Breastfeeding can resume once the mother is awake; follow the advice for the other anaesthetic drugs used.
報告されている副作用
- Slight elevation in pulse rate
- Elevations in blood pressure
禁忌
- Hypersensitive to drug or excipients
- Use in neonates, including premature infants, (formulation contains benzyl alcohol)
注意が必要な方
- Additive/synergistic effects if administered with or following an opioid, sedative or anesthetic agent
- Use caution in patients with poor renal perfusion or severe renal disease, preexisting tachycardia
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (145)
- Amikacin + Pancuronium Major
- Bacitracin-neomycin-polymyxin + Pancuronium Major
- Capreomycin + Pancuronium Major
- Clindamycin + Pancuronium Major
- Colistin + Pancuronium Major
- Dexamethasone-tobramycin + Pancuronium Major
- Gentamicin + Pancuronium Major
- Lincomycin + Pancuronium Major
- Magnesium + Pancuronium Major
- Magnesium sulfate + Pancuronium Major
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Pancuroniumの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
- IV preparation and dilution
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同じ分類のほかの薬剤
よくある質問
What is Pancuronium used for?
Pancuronium is a medicine in the class musculoskeletal. It is used for Cesarean section, Endotracheal intubation, General anesthesia adjunct.
What side effects have been reported with Pancuronium?
Slight elevation in pulse rate, Elevations in blood pressure.
Can Pancuronium be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Long-acting muscle relaxant used in anaesthesia, including caesarean section; only small amounts cross the placenta. Its effect can be prolonged by magnesium sulphate. Acceptable for anaesthesia when needed. Breastfeeding: Safe. No milk data, but it is highly polar and poorly absorbed by mouth, so little is likely to reach milk or the infant (LactMed). Breastfeeding can resume once the mother is awake; follow the advice for the other anaesthetic drugs used.
What does Pancuronium interact with?
MediHelp lists 145 known interactions for Pancuronium. Major: 14 · Moderate: 73 · Minor: 58. The most serious include Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
