相互作用
Capreomycin + Pancuronium
重症度: 重大
Capreomycin and Pancuronium: major interaction.
最終更新日
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概要
Capreomycin has neuromuscular blocking activity and can potentiate and prolong pancuronium paralysis. This can cause delayed recovery and respiratory depression or apnea.
この相互作用をわかりやすく説明すると
Capreomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Capreomycin has curare-like neuromuscular blocking action that adds to nondepolarizing blockade.
対処法
Avoid combining if possible; otherwise reduce pancuronium dose, monitor with train-of-four and keep ventilatory support available through recovery.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CapreomycinとPancuroniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Pancuroniumのその他の相互作用
よくある質問
Can I take Capreomycin with Pancuronium?
MediHelp rates the interaction as major. Capreomycin and Pancuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Capreomycin has neuromuscular blocking activity and can potentiate and prolong pancuronium paralysis. This can cause delayed recovery and respiratory depression or apnea.
How serious is the interaction between Capreomycin and Pancuronium?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining if possible; otherwise reduce pancuronium dose, monitor with train-of-four and keep ventilatory support available through recovery.
What other medicines interact with Pancuronium?
MediHelp also lists interactions of Pancuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Clindamycin. The full list is on the Pancuronium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
