相互作用
Abiraterone + Cannabidiol
重症度: 中等度
Abiraterone and Cannabidiol: moderate interaction.
最終更新日
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概要
Abiraterone may inhibit CYP2C19 and raise cannabidiol exposure, increasing sedation, somnolence and liver enzyme elevations. The effect is predicted from mechanism.
この相互作用をわかりやすく説明すると
Abiraterone and Cannabidiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Abiraterone belongs to Endocrine; Cannabidiol belongs to Central Nervous System.
なぜ起こるのか
Abiraterone inhibits CYP2C19, reducing cannabidiol metabolism.
対処法
Monitor for sedation and adverse effects and liver enzymes; reduce cannabidiol dose if adverse effects occur.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AbirateroneとCannabidiolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Abirateroneのその他の相互作用
Cannabidiolのその他の相互作用
よくある質問
Can I take Abiraterone with Cannabidiol?
MediHelp rates the interaction as moderate. Abiraterone and Cannabidiol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Abiraterone may inhibit CYP2C19 and raise cannabidiol exposure, increasing sedation, somnolence and liver enzyme elevations. The effect is predicted from mechanism.
How serious is the interaction between Abiraterone and Cannabidiol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sedation and adverse effects and liver enzymes; reduce cannabidiol dose if adverse effects occur.
What other medicines interact with Abiraterone?
MediHelp also lists interactions of Abiraterone with, for example, Radium-223 dichloride, Thioridazine, Amobarbital. The full list is on the Abiraterone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
