相互作用
Aclidinium + Oxybutynin
重症度: 中等度
Aclidinium and Oxybutynin: moderate interaction.
最終更新日
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概要
Both are antimuscarinic agents, so combined use may add anticholinergic effects such as dry mouth, constipation, urinary retention and blurred vision. Systemic exposure to inhaled aclidinium is low, limiting the effect.
この相互作用をわかりやすく説明すると
Aclidinium and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive muscarinic receptor antagonism.
対処法
Monitor for urinary retention, constipation and angle-closure glaucoma symptoms, particularly in older patients.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AclidiniumとOxybutyninの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Oxybutyninのその他の相互作用
よくある質問
Can I take Aclidinium with Oxybutynin?
MediHelp rates the interaction as moderate. Aclidinium and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both are antimuscarinic agents, so combined use may add anticholinergic effects such as dry mouth, constipation, urinary retention and blurred vision. Systemic exposure to inhaled aclidinium is low, limiting the effect.
How serious is the interaction between Aclidinium and Oxybutynin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation and angle-closure glaucoma symptoms, particularly in older patients.
What other medicines interact with Oxybutynin?
MediHelp also lists interactions of Oxybutynin with, for example, Bethanechol, Clozapine, Potassium chloride. The full list is on the Oxybutynin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
