相互作用
Bethanechol + Oxybutynin
重症度: 重大
Bethanechol and Oxybutynin: major interaction.
最終更新日
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概要
Oxybutynin is an antimuscarinic bladder relaxant that directly opposes bethanechol's detrusor stimulation, so the therapeutic effect of each is reduced.
この相互作用をわかりやすく説明すると
Bethanechol and Oxybutynin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bethanechol belongs to Gastrointestinal Tract; Oxybutynin belongs to Genitourinary.
なぜ起こるのか
Competitive muscarinic antagonism by oxybutynin against bethanechol agonism.
対処法
Avoid combining; reassess the bladder indication and use only one agent.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BethanecholとOxybutyninの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bethanecholのその他の相互作用
Oxybutyninのその他の相互作用
よくある質問
Can I take Bethanechol with Oxybutynin?
MediHelp rates the interaction as major. Bethanechol and Oxybutynin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Oxybutynin is an antimuscarinic bladder relaxant that directly opposes bethanechol's detrusor stimulation, so the therapeutic effect of each is reduced.
How serious is the interaction between Bethanechol and Oxybutynin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining; reassess the bladder indication and use only one agent.
What other medicines interact with Bethanechol?
MediHelp also lists interactions of Bethanechol with, for example, Darifenacin, Fesoterodine, Physostigmine. The full list is on the Bethanechol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
