相互作用
Adrenaline-articaine + Ergotamine
重症度: 重大
Adrenaline-articaine and Ergotamine: major interaction.
最終更新日
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概要
Epinephrine and ergotamine are both strong vasoconstrictors. Added together, severe hypertension and ischaemia of the extremities or brain become possible.
この相互作用をわかりやすく説明すると
Adrenaline-articaine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Adrenaline-articaine belongs to Central Nervous System; Ergotamine belongs to Central Nervous System.
なぜ起こるのか
Additive alpha-adrenergic and serotonergic vasoconstriction
対処法
Avoid epinephrine-containing anaesthetics in patients taking ergotamine where possible; use minimal dose if unavoidable and monitor.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Adrenaline-articaineとErgotamineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Adrenaline-articaineのその他の相互作用
Ergotamineのその他の相互作用
よくある質問
Can I take Adrenaline-articaine with Ergotamine?
MediHelp rates the interaction as major. Adrenaline-articaine and Ergotamine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Epinephrine and ergotamine are both strong vasoconstrictors. Added together, severe hypertension and ischaemia of the extremities or brain become possible.
How serious is the interaction between Adrenaline-articaine and Ergotamine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid epinephrine-containing anaesthetics in patients taking ergotamine where possible; use minimal dose if unavoidable and monitor.
What other medicines interact with Adrenaline-articaine?
MediHelp also lists interactions of Adrenaline-articaine with, for example, Clozapine, Dihydroergotamine, Dihydroergotamine intranasal. The full list is on the Adrenaline-articaine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
