相互作用
Almotriptan + Naratriptan
重症度: 併用禁忌
Almotriptan and Naratriptan: contraindicated interaction.
最終更新日
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概要
Two 5-HT1B/1D agonists (naratriptan, almotriptan) given close together add coronary and peripheral vasoconstriction. Prolonged vasospasm and ischaemic events may occur.
この相互作用をわかりやすく説明すると
Almotriptan and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Almotriptan belongs to Central Nervous System; Naratriptan belongs to Central Nervous System.
なぜ起こるのか
Additive 5-HT1B/1D-mediated vasoconstriction
対処法
Do not take another triptan within 24 hours of almotriptan; space doses accordingly.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、AlmotriptanとNaratriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Naratriptanのその他の相互作用
Almotriptanのその他の相互作用
よくある質問
Can I take Almotriptan with Naratriptan?
MediHelp rates the interaction as contraindicated. Almotriptan and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Two 5-HT1B/1D agonists (naratriptan, almotriptan) given close together add coronary and peripheral vasoconstriction. Prolonged vasospasm and ischaemic events may occur.
How serious is the interaction between Almotriptan and Naratriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not take another triptan within 24 hours of almotriptan; space doses accordingly.
What other medicines interact with Naratriptan?
MediHelp also lists interactions of Naratriptan with, for example, Dihydroergotamine intranasal, Dihydroergotamine, Eletriptan. The full list is on the Naratriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。