医薬品リファレンス
Naratriptan
Naratriptan is a medicine in the class central nervous system. It is used for migraine.
- 薬効分類: Central Nervous System
- 効能・効果: migraine
最終更新日
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要点
- 薬効分類
- Central Nervous System
- 一般的な剤形
- 錠剤
- 一般的な規格
- 2.5 mg
- 既知の相互作用
- 113 (併用禁忌: 8 · 重大: 11 · 中等度: 69 · 軽度: 25)
- 商品名
- 3
- 国・市場
- 2
何に使われるか
作用のしくみ
Selective 5-HT1 receptor agonist in cranial arteries Causes vasoconstriction and reduces inflammation associated with antidronic neuronal transmission associated with relief of migraine
成人の通常用量（添付文書の要約）
1-2.5 mg PO at onset; may repeat once after 4 hours, Not to exceed 5 mg/day
妊娠と授乳
- 妊娠
- Unknown Small registry and cohort data are too few to judge, though triptan registries (mainly sumatriptan) show no rise in birth defects. In animals it caused embryo death and fetal abnormalities at 2.5 to 11 times human exposure. Use only if needed; sumatriptan has the most pregnancy data.
- 授乳
- Unknown No human milk data; present in rat milk. UK label: avoid breastfeeding for 24 hours after a dose. Triptans can occasionally cause painful nipples. LactMed: not a reason to stop breastfeeding an older infant, but an alternative may be preferred with a newborn.
報告されている副作用
- Drowsiness
- Fatigue
- Nausea
- Dizziness
- Paresthesias
- Pain/pressure sensation
注意が必要な方
- Reports of transient and permanent blindness and significant partial vision loss reported with the use of 5-HT1 agonists; since visual disorders may be part of a migraine
- Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (113)
- Almotriptan + Naratriptan Contraindicated
- Dihydroergotamine + Naratriptan Contraindicated
- Dihydroergotamine intranasal + Naratriptan Contraindicated
- Eletriptan + Naratriptan Contraindicated
- Ergoloid mesylates + Naratriptan Contraindicated
- Ergotamine + Naratriptan Contraindicated
- Frovatriptan + Naratriptan Contraindicated
- Methylergonovine + Naratriptan Contraindicated
- Isocarboxazid + Naratriptan Major
- Linezolid + Naratriptan Major
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Naratriptanの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Dosing in older adults
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Naratriptan used for?
Naratriptan is a medicine in the class central nervous system. It is used for Migraine.
What side effects have been reported with Naratriptan?
Drowsiness, Fatigue, Nausea, Dizziness, Paresthesias, Pain/pressure sensation.
Can Naratriptan be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Small registry and cohort data are too few to judge, though triptan registries (mainly sumatriptan) show no rise in birth defects. In animals it caused embryo death and fetal abnormalities at 2.5 to 11 times human exposure. Use only if needed; sumatriptan has the most pregnancy data. Breastfeeding: Unknown. No human milk data; present in rat milk. UK label: avoid breastfeeding for 24 hours after a dose. Triptans can occasionally cause painful nipples. LactMed: not a reason to stop breastfeeding an older infant, but an alternative may be preferred with a newborn.
What does Naratriptan interact with?
MediHelp lists 113 known interactions for Naratriptan. Contraindicated: 8 · Major: 11 · Moderate: 69 · Minor: 25. The most serious include Almotriptan, Dihydroergotamine, Dihydroergotamine intranasal.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
