相互作用
Dihydroergotamine + Naratriptan
重症度: 併用禁忌
Dihydroergotamine and Naratriptan: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Naratriptan and dihydroergotamine each cause vasoconstriction, and together they may prolong vasospastic reactions. This can cause cardiac, cerebral or peripheral ischemia.
この相互作用をわかりやすく説明すると
Dihydroergotamine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Naratriptan belongs to Central Nervous System.
なぜ起こるのか
Additive vasoconstriction via 5-HT1B/1D agonism and ergot vascular receptor effects.
対処法
Do not use together and keep at least 24 hours between them. Use one agent per attack.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DihydroergotamineとNaratriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Naratriptanのその他の相互作用
Dihydroergotamineのその他の相互作用
よくある質問
Can I take Dihydroergotamine with Naratriptan?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Naratriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Naratriptan and dihydroergotamine each cause vasoconstriction, and together they may prolong vasospastic reactions. This can cause cardiac, cerebral or peripheral ischemia.
How serious is the interaction between Dihydroergotamine and Naratriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together and keep at least 24 hours between them. Use one agent per attack.
What other medicines interact with Naratriptan?
MediHelp also lists interactions of Naratriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Eletriptan. The full list is on the Naratriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
